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By Jessica Hamzelou. The dramatic transition from womb to world is the time when a baby ingests some of the first bacteria that will colonise its guts. But babies born by C-section miss out on this process, and end up with a different set of bugs — including some from the hospital environment. A number of studies have found evidence that this C-section microbiome could make the child more vulnerable to problems later in life, such as asthma , food allergies, hay fever and obesity. We are still getting to grips with just how important the collection of bacteria in our guts — and other body sites — are for our health.
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Colorectal bacteria may play a role in the pathogenesis of inflammatory bowel disease IBD. To test the hypothesis that, in affected patients, the numbers of potentially protective mucosal bacteria might be reduced and pathogenic species increased, we compared rectal mucosa-associated flora in patients with IBD and normal controls. Snap-frozen rectal biopsies taken at routine diagnostic colonoscopy from 33 patients with ulcerative colitis, 6 patients with Crohn's disease, and 14 controls with normal colonoscopy were processed, and individual bacterial groups were counted using fluorescent in situ hybridization. Bacteria were mostly found apposed to the epithelial surface and within crypts. Epithelium-associated E. Numbers of Lactobacillus and Bacteroides showed no differences between patient groups.
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The digestive system works by pushing food through the intestines which usually takes between 24 to 72 hours. Muscular contractions squeeze peristalsis the food through the different sections of the intestine. These different sections are separated by bands of muscles, or sphincters, which act as valves. The passage of food from one area of the intestines to another is coordinated so that food stays in a specific area for long enough for the gut to do a particular job — absorb fluids and nutrients, or process and expel waste. Food passes from the stomach into the duodenum, which is the tube that leads from the stomach into the intestines.
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The case studies and evidence-based practice dialogues provide great opportunities for further reflection. The book is useful to a wide audience in nursing, including undergraduate and graduate nursing students, practicing neonatal and pediatric nurses, and advanced practice nurses who care for neonates. The sixth edition of this acclaimed neonatal nursing text is completely updated to encompass the most current research findings and strategies for providing cost-effective and evidence-based care. It continues to address neonatal care from a physiologic and pathophysiologic perspective, with a major emphasis on nursing management at the bedside and advanced practice level.
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