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Download page FTP site. You might have noticed some additional information on the mature miRNA pages in the last few weeks. After repeated and unreasonable delay, miRBase 22 is finally released. As you might expect with such a long gap, the number of sequences in the database has jumped significantly — by over a third. The vast majority of the increase comes from new microRNA annotations in species not previous represented in the database.
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These unique papers were originally read at a conference on the new economic history of Britain at Harvard in , and each is accompanied by a summary of the discussion that followed it. The participants of the conference represented a broad range of scholars from both sides of the Atlantic. The first eleven papers deal with a variety of topics covering a period from to the s. They focus on the performance of the British economy, and especially its businessmen, during the time of Britain's industrial maturity and relative decline. The papers and discussions reached a novel conclusion tha, contrary to commonly held opinion, the British economy performed well and that British businessmen were not lacking in entrepreneurial vigour compared with their German or American counterparts. But even more important for British historiography than this finding was the demonstration that economic and statistical methods can be applied successfully to the study of economic history. The papers in the concluding section discuss the origins and development of the new economic history and show that, as a substantial supplement to work along more traditional lines, its methods and application are both desirable and possible.
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These slow-growing tumors contain elements from multiple germ cell layers and are best assessed with ultrasound. Although they have very similar imaging appearances, the two have a fundamental histological difference: a dermoid is composed only of dermal and epidermal elements which are both ectodermal in origin , whereas teratomas also comprise mesodermal and endodermal elements. For the sake of simplicity, both are discussed in this article, as much of the literature combines the two entities. Uncomplicated ovarian dermoid tend to be asymptomatic and are often discovered incidentally. They do, however, predispose to ovarian torsion , and may then present with acute pelvic pain.
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